University of Cambridge PhD Studentship in Biostatistics/Applied Statistics
A PhD studentship in Biostatistics/Applied Statistics is available in a new interdisciplinary research programme in population health and genomics. The studentship will focus on developing stratified approaches to recommending the intervals at which particular groups of blood donors should be able to give blood. The project will be based on the INTERVAL study, a major randomized trial in which 50,000 male and female blood donors in the UK are randomized to give blood at, or more frequently than, the standard intervals (8 and 10 weeks vs the standard 12-weeks for men, and 12 and 14 weeks vs the standard 16-weeks for women). The outcomes in the trial are the amount of blood collected over the two years of the trial, the number of deferrals (temporary rejection of a donor due to low haemoglobin), quality of life and adverse events. In addition to the overall comparison of randomised groups, interest centres on whether different inter-donation intervals should be recommended for people with different characteristics (e.g. by age, weight, blood biomarkers, or genetic characteristics).
It is envisaged this studentship will involve:
delineating which donors benefit most based on single and multiple baseline characteristics;
developing statistical methodology for model selection and data reduction techniques;
examining methods for internal and/or external validation of such stratified groupings;
incorporating complex genetic information into stratification schemes;
comparing simple and complex stratification schemes both in terms of their overall efficiency in increasing benefit/decreasing harm, and in terms of their potential for practical implementation.
Applications for this scheme should include:
A CV, including full details of all University courses taken with date, with grades if available.
The names and contact details of three academic referees.
A covering letter (up to 500 words) explaining why you wish to be considered for this particular studentship, what you will bring to the project and listing any relevant research experience to date.
The scheme is open to nationals from all countries, but fees can only be provided at the Home/EU rate. Applicants should have excellent grades (ideally a first-class degree or distinction in a Masters degree) in a subject that relates to the goals of the Research Unit (eg, biostatistics).
Further information, including details of specific projects are available at http://www.phpc.cam.ac.uk/ceu/research/phd-population-health/
Applications should be emailed to Sean Hickin (email@example.com) All applications must be received by midnight on 10th January 2016. Earlier applications are encouraged. Shortlisted candidates can expect to be interviewed week commencing 18th January 2016 Please quote reference RH07695 on your application and in any correspondence about this vacancy. The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.