Applications are invited for a three-year PhD studentship position funded by the Department of Pathology to start from January 2018.
The successful candidate will join Dr Stephen Graham's laboratory to investigate the mechanisms by which viruses modify cellular membranes during infection. Our lab has recently identified a number of novel interactions between herpesvirus proteins and cellular factors that modulate host-cell membrane composition and the trafficking of cellular membrane proteins. This project aims to define the molecular basis of these interactions and their contribution to virus infection. This will be achieved by combining structural, biochemical and cell biology techniques including: atomic-resolution structures of the herpesvirus proteins alone and in complexes with their cellular partners, biophysics to define the molecular details such protein:protein interactions, fluorescence microscopy to localise these complexes within cells, and production of recombinant viruses to the function of these proteins during virus infection. The successful applicant will join a vibrant multidisciplinary research team that aims to provide the underpinning science for the next generation of therapeutic agents.
The deadline for applications is 26th July 2017. Informal enquires regarding this studentship may be made to Dr Stephen Graham email@example.com. General queries should be directed to firstname.lastname@example.org or 01223 333940.
Please quote reference PK12089 on your application and in any correspondence about this vacancy.
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