Marie Curie PhD Fellowship in Optimization of Screw Constructs for Spinal Applications 2019, Uppsala University, Sweden

Uppsala University


June 28, 2019

Marie Curie PhD position in Optimization of screw constructs for spinal applications

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our mission is to pursue top-quality research and education and to interact constructively with society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has 44.000 students, 7.100 employees and a turnover of SEK 7 billion.

The Department of Engineering Sciences is one of the largest at Uppsala University and conducts research within a number of different technical subjects. The department has approximately 360 employees and has its activities at the Ångström Laboratory and Campus Gotland.

The Marie Curie-PhD position is at the Division of Applied Materials Science, the Ångström Laboratory.

We are pleased to invite applications for a Marie Curie-PhD position in the new four-year EU-funded Marie Sklodowska-Curie ITN programme “Training innovative future leaders in research and development of materials and implants for the spine” (NU-SPINE,, project ID 812 765). This network is led by Prof. Cecilia Persson at Uppsala University and consists of three European universities (Uppsala University, ETH Zürich and University of Leeds) as well as industrial (IHI Ionbond AG, CeramTec GmbH, Key Engineering Solutions, SINTX Technologies and OssDsign AB) and clinical (Leeds Teaching Hospitals NHS Trust) collaborators.

Project description: NU-SPINE aims to deliver novel material compositions with a higher degree of biocompatibility as well as novel implant designs adapted to the local loading situation. Important deliverables for the network are also innovative methods for more accurate evaluation of the demanding tribological and corrosive conditions surrounding the implants. NU-SPINE will train talented researchers with the scientific and entrepreneurial mind required of the next generation of leaders in academia and industry connected to these medical devices. As a Marie Curie-PhD student, you will benefit from a tailored, multidisciplinary, scientific training programme, and be exposed to different environments via planned placements, and contribute to and organise workshops.

This Marie Curie-PhD project will focus on the development of validated numerical models for optimization of screw design and bone augmentation as a function of surrounding bone morphology. The project will (i) increase the understanding of failure mechanisms of a screw/bone and screw/bone/cement constructs, at the microscale, (2) produce 3-dimensional, validated numerical models of screw pull-outs in human bone and (3) develop novel screw and screw augmentation designs and recommendations, better adapted to the microstructure of the surrounding bone. The project will be performed mainly at Uppsala University. Main supervision will be undertaken by Prof Cecilia Persson (Uppsala University), with co-supervision from Prof Per Isaksson (Uppsala University) and Dr Jonas Åberg (OssDsign AB). The position includes secondments at ETH Zürich, Switzerland (5 months) and OssDsign, Sweden (1 month).

Your main duties will include:

  • Conducting world-class research focussed on materials development and implant design for spinal applications and NU-SPINE activities
  • Developing initiative, creativity and judgement in applying appropriate approaches to research activities
  • Actively participate in all relevant activities organised by the network as advised by the Supervisor
  • Attending meetings as required to discuss the project. This will involve occasional EU-wide travel, beyond that associated with secondments
  • Ensuring good day-to-day progress of work, and maintaining good records
  • Writing up results for publication and attending suitable conferences for their dissemination
  • Working both independently and also as part of a larger team of researchers, including interacting with and providing assistance to other staff in the research group and the NU-SPINE network and engaging in knowledge-transfer activities where appropriate and feasible
  • Contributing to joint discussions within the wider research group and network
  • Maintaining your own continuing professional development

These duties provide a framework for the role and should not be regarded as a definitive list. Other reasonable duties may be required consistent with the grade of the post.

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Publish Date
June 24, 2019