PhD Research Fellowship in Analytical Chemistry
A position as PhD Research fellow is available at School of Pharmacy. The fellowship is for a period of up to 3 years. Starting date no later than 01.05.2017. No one can be appointed for more than one fixed-term period at the same institution.
Project description
Small Cell Lung Cancer (SCLC) is an aggressive form of lung cancer (1 out of 5 lung cancers) with a short survival after diagnosis (few months). Since SCLC is sensitive for treatment, early diagnosis or proper monitoring is of high interest. Our research focuses on design of the sample preparation and the possibility to determine multiple SCLC markers simultaneously at ultra low concentrations as well as the possibility to differentiate between existing isovariants which might allow a more robust and personalized diagnostic profile in the future.
During the project the candidate will work with implementing Molecular Imprinted Polymers in the sample preparation step of bottom-up LC-MS analysis of validated ultra low abundant biomarkers for SCLC.
The project will include secondments to University of Southern Denmark, Odense (DK), Cancer Research UK Manchester (UK), Proteome Sciences, London (UK), ReSyn Biosciences, Gauteng (South Africa) – bioanalytical techniques, biomarker assays, modification specific proteomics; Linneaus University (Sweden) and Pavia University (Italy) - theoretical modeling and characterization; University of Strathclyde, Glasgow (UK) and Federal Institute for Materials Research, BAM, Berlin (Germany) – molecular imprinting and sensor technology. The secondments will allow the candidate to work with and oversee the implementation of the materials and to gain insight into academic and industrial work environments.
Research network description
BioCapture is a European Training Network (ETN) funded by the European Commission under the Horizon 2020 Marie Skłodowska-Curie Action. 15 research groups, spread across 11 universities and institutes and 4 industrial partners in 6 different countries have come together to train a new generation of chemists/phycisists/biologists through an EU-wide PhD training network. The candidate will work in the Bioanalysis group at the University of Oslo which carries out research in the field of targeted protein analysis using LC-MS/MS. The main focus is on the sample preparation and clean-up step to allow determination of extreme low amounts of biomarkers in complex biological samples like plasma and blood. The group is linked to the prioritized research initiative DIATECH.
Requirements and qualifications
Applicants must hold a Master's degree or equivalent in (bio)analytical chemistry at the moment of appointment. The candidate should be familiar with bottom-up proteomics analysis and have experience with techniques and procedures like HPLC, nano LC, LC-MS/MS, tryptic digestion of proteins, sample preparation of biological samples (both SPE and immunobased techniques). Knowledge of polymer chemistry in general and molecular imprinting technology in special is advantageous.
To be eligible, each researcher must simultaneously fulfill the following criteria at the time of recruitment by the beneficiary concerned in the frame of this project.
(a) Nationality: The researcher may be a national of a Member State of the Union, of an Associated Country or of any other third country.
(b) Mobility: At the time of selection by the host organization, the researcher may not have resided or carried out his/her main activity in the country of the beneficiary for more than 12 months in the 3 years immediately prior to his/her appointment. Short stays such as holidays are not taken into account.
As far as international European interest organizations or international organizations are concerned, this rule does not apply to the hosting of eligible researchers, however the appointed researcher must not have spent more than 12 months in the 3 years immediately prior to the selection by the host organization in the same appointing organization
The Faculty of Mathematics and Natural Sciences has a strategic ambition of being a leading research faculty. Candidates for these fellowships will be selected in accordance with this, and expected to be in the upper segment of their class with respect to academic credentials.
The purpose of the fellowship is research training leading to the successful completion of a PhD degree.
The fellowship requires admission to the PhD program at the Faculty of Mathematics and Natural Sciences. The application to the PhD program must be submitted to the department no later than two months after taking up the position.
A good command of English is required.
Salary:
Position code 1017, Salary: NOK 432 700 – 489 300 per year, depending on qualifications and seniority.
The application must include:
- Application letter
- CV (summarizing education, positions and academic work - scientific publications)
- Copies of educational certificates, transcript of records and letters of recommendation
- Documentation of English proficiency
- List of publications and academic work that the applicant wishes to be considered by the evaluation committee
- Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number)
Foreign applicants are advised to attach an explanation of their University's grading system. Please remember that all documents should be in English or a Scandinavian language.
In accordance with the University of Oslo's equal opportunities policy, we invite applications from all interested individuals regardless of gender or ethnicity.
To APPLY click "LINK TO ORIGINAL" below.
This opportunity has expired. It was originally published here:
http://uio.easycruit.com/vacancy/1739951/64281?iso=no